PRMT2 Polyclonal Antibody from MyBioSource.com

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PRMT2 Polyclonal Antibody

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The PRMT2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PRMT2. This antibody recognizes Human, Mouse, and Rat antigen. The PRMT2 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.

Description

Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation